Neuro-Ophthalmology Lab

Sun Yat-sen University

State Key Laboratory of Ophthalmology

tianxiang Tu

涂天祥

Position：

PhD Student

Email:

tusantiaowmu@163.com

Education

He joined the Neuro-ophthalmology Lab as a Ph.D. student in 2023

M.M. in ophthalmology , Wenzhou Medical University, 2022

M.D in North China University of Science and Technology, 2018

Research Interest

His research focuses on the modification of gene editing tools, especially in adenine base editors.

Publication：

Tu T, Song Z, Liu X, Wang S, He X, Xi H, Wang J, Yan T, Chen H, Zhang Z, Lv X, Lv J, Huang XF, Zhao J, Lin CP, Gao C, Zhang J, Gu F. A precise and efficient adenine base editor. Mol Ther. 2022 Sep 7;30(9):2933-2941. doi: 10.1016/j.ymthe.2022.07.010.

Fu J, Li Q, Liu X, Tu T, Lv X, Yin X, Lv J, Song Z, Qu J, Zhang J, Li J, Gu F. Human cell based directed evolution of adenine base editors with improved efficiency. Nat Commun. 2021 Oct 8;12(1):5897. doi: 10.1038/s41467-021-26211-0.

Zhao T, Li Q, Zhou C, Lv X, Liu H, Tu T, Tang N, Cheng Y, Liu X, Liu C, Zhao J, Song Z, Wang H, Li J, Gu F. Small-molecule compounds boost genome-editing efficiency of cytosine base editor. Nucleic Acids Res. 2021 Sep 7;49(15):8974-8986. doi: 10.1093/nar/gkab645.

Li F, Zhou C, Tu T, Liu Y, Lv X, Wang B, Song Z, Zhao Q, Liu C, Gu F, Zhao J. Rational Selection of CRISPR-Cas Triggering Homology-Directed Repair in Human Cells. Hum Gene Ther. 2021 Mar;32(5-6):302-309. doi: 10.1089/hum.2020.247.

Lv X, Qiu K, Tu T, He X, Peng Y, Ye J, Fu J, Deng R, Wang Y, Wu J, Liu C, Zhao J, Gu F. Development of a Simple and Quick Method to Assess Base Editing in Human Cells. Mol Ther Nucleic Acids. 2020 Jun 5;20:580-588. doi: 10.1016/j.omtn.2020.03.004.